Antiplatelets, clopidogrel - Side effects of clopidogrel

Clopidogrel can cause side effects, although serious reactions are rare.

Common side effects of clopidogrel can include:

• headaches or dizziness
• nausea
• diarrhoea or constipation
• indigestion (dyspepsia)
• stomach ache or abdominal pain 
• nosebleeds 
• increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising

Speak to your GP if any of these side effects get worse or don't go away.

Although clopidogrel is unlikely to affect your ability to drive, some people may feel dizzy when taking it. Avoid driving if you feel dizzy.

Serious side effects

More serious side effects can include:

• rashes and itching
• severe stomach ache or abdominal pain
• uncontrolled bleeding or unusual bruising
• vomiting with blood
• weakness or numbness in an arm or leg
• blood in your urine (haematuria) 
• blood in your stools

Speak to your GP or call NHS 111 immediately if you experience any of these side effects or any other unusual problems while taking clopidogrel.

Allergic reaction

In some cases clopidogrel can cause an allergic reaction. Go to the nearest hospital's accident and emergency department (A&E) if you experience:

• swelling of the lips, mouth or throat
• breathing problems
• a skin rash that appears quickly